Publikationen 2023
Ahmad I, Lokau J, Kespohl B, Malik NA, Baig SM, Hartig R, Behme D, Schwab R, Altmüller J, Jameel M, Mucha S, Thiele H, Tariq M, Nürnberg P, Erdmann J, Garbers C.
The interleukin-11 receptor variant p.W307R results in craniosynostosis in humans.
Sci Rep. 2023 Aug 18;13(1):13479.
Baars I, Jaedtka M, Dewitz LA, Fu Y, Franz T, Mohr J, Gintschel P, Berlin H, Degen A, Freier S, Rygol S, Schraven B, Kahlfuß S, van Zandbergen G, Müller AJ.
Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate.
JCI Insight. 2023 Jul 24;8(14):e169020.
Baur R, Karl F, Böttcher-Loschinski R, Stoll A, Völkl S, Gießl A, Flamann C, Bruns H, Schlötzer-Schrehardt U, Böttcher M, Schewe DM, Fischer T, Jitschin R, Mackensen A, Mougiakakos D.
Accumulation of T-cell-suppressive PD-L1high extracellular vesicles is associated with GvHD and might impact GvL efficacy.
J Immunother Cancer. 2023 Mar;11(3):e006362.
Bernhardt A, Krause A, Reichardt C, Steffen H, Isermann B, Völker U, Hammer E, Geffers R, Philipsen L, Dhjamandi K, Ahmad S, Brandt S, Lindquist JA, Mertens PR.
Excessive sodium chloride ingestion promotes inflammation and kidney fibrosis in aging mice.
Am J Physiol Cell Physiol. 2023 Aug 1;325(2):C456-C470.
Binder R, Hahn A, Eberhardt KA, Hagen RM, Rohde H, Loderstädt U, Feldt T, Sarfo FS, Di Cristanziano V, Kahlfuss S, Frickmann H, Zautner AE.
Comparison of the Diagnostic Accuracy of Three Real-Time PCR Assays for the Detection of Arcobacter butzleri in Human Stool Samples Targeting Different Genes in a Test Comparison without a Reference Standard.
Microorganisms. 2023 May 17;11(5):1313.
Brauns S, Marquardt I, Thon C, Frentzel S, Jakob J, Färber J, Philipsen L, Jänsch L, Link A, Bruder D.
Mucosal-associated invariant T (MAIT) cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity.
Int Immunol. 2023 Aug 7:dxad032.
Cammann C, Kulla J, Wiebusch L, Walz C, Zhao F, Lowinus T, Topfstedt E, Mishra N, Henklein P, Bommhardt U, Bossaller L, Hagemeier C, Schadendorf D, Schmidt B, Paschen A, Seifert U.
Proteasome inhibition potentiates Kv1.3 potassium channel expression as therapeutic target in drug-sensitive and -resistant human melanoma cells.
Biomed Pharmacother. 2023 Oct 8;168:115635.
Dubiel D, Wang J, Hartig R, Chaithongyot S, Dubiel W, Naumann M.
Latent CSN-CRL complexes are crucial for curcumin-induced apoptosis and recruited during adipogenesis to lipid droplets via small GTPase RAB18.
iScience. 2023 Mar 22;26(4):106468.
Fischer V, Bülow JM, Krüger BT, Ragipoglu D, Vikman A, Haffner-Luntzer M, Katsoulis-Dimitriou K, Dudeck A, Ignatius A.
Role of Mast-Cell-Derived RANKL in Ovariectomy-Induced Bone Loss in Mice.
Int J Mol Sci. 2023 May 23;24(11):9135.
Guttek K, Reinhold A, Grüngreiff K, Schraven B, Reinhold D.
Zinc aspartate induces proliferation of resting and antigen-stimulated human PBMC under high-density cell culture condition.
J Trace Elem Med Biol. 2023 Mar 11;77:127152.
Haage TR, Schraven B, Mougiakakos D, Fischer T.
How ITD Insertion Sites Orchestrate the Biology and Disease of FLT3-ITD-Mutated Acute Myeloid Leukemia.
Cancers (Basel). 2023 May 30;15(11):2991.
Hoffmann K, Riediger M, Tersteegen A, Marquardt P, Kahlfuß S, Kaasch AJ, Hagen RM, Frickmann H, Zautner AE.
Molecular epidemiology of enterically colonizing Escherichia coli with resistance against third-generation cephalosporins isolated from stool samples of European soldiers with concomitant diarrhea on deployment in Western African Mali.
Front Microbiol. 2023 May 5;14:1169829.
Jantz-Naeem N, Böttcher-Loschinski R, Borucki K, Mitchell-Flack M, Böttcher M, Schraven B, Mougiakakos D, Kahlfuss S.
TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment.
Front Oncol. 2023 Feb 17;13:1060112.
Karl F, Liang C, Böttcher-Loschinski R, Stoll A, Flamann C, Richter S, Lischer C, Völkl S, Jacobs B, Böttcher M, Jitschin R, Bruns H, Fischer T, Holler E, Rösler W, Dandekar T, Mackensen A, Mougiakakos D.
Oxidative DNA damage in reconstituting T cells is associated with relapse and inferior survival after allo-SCT.
Blood. 2023 Mar 30;141(13):1626-1639.
Keller B, Kfir-Erenfeld S, Matusewicz P, Hartl F, Lev A, Lee YN, Simon AJ, Stauber T, Elpeleg O, Somech R, Stepensky P, Minguet S, Schraven B, Warnatz K.
Combined Immunodeficiency Caused by a Novel Nonsense Mutation in LCK.
J Clin Immunol. 2023 Dec 19;44(1):4.
Kespohl B, Hegele AL, Düsterhöft S, Bakker H, Buettner FFR, Hartig R, Lokau J, Garbers C.
Molecular characterization of the craniosynostosis-associated interleukin-11 receptor variants p.T306_S308dup and p.E364_V368del.
FEBS J. 2023 Nov 22. Epub ahead of print.
Kruse B, Buzzai AC, Shridhar N, Braun AD, Gellert S, Knauth K, Pozniak J, Peters J, Dittmann P, Mengoni M, van der Sluis TC, Höhn S, Antoranz A, Krone A, Fu Y, Yu D, Essand M, Geffers R, Mougiakakos D, Kahlfuß S, Kashkar H, Gaffal E, Bosisio FM, Bechter O, Rambow F, Marine JC, Kastenmüller W, Müller AJ, Tüting T.
CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours.
Nature. 2023 Jun 14.
Lindquist JA, Bernhardt A, Reichardt C, Sauter E, Brandt S, Rana R, Lindenmeyer MT, Philipsen L, Isermann B, Zhu C, Mertens PR.
Cold Shock Domain Protein DbpA Orchestrates Tubular Cell Damage and Interstitial Fibrosis in Inflammatory Kidney Disease.
Cells. 2023 May 19;12(10):1426. doi: 10.3390/cells12101426.
Ludewig S, Salzburger L, Goihl A, Rohne J, Leypoldt F, Bittner D, Düzel E, Schraven B, Reinhold D, Korte M, Körtvélyessy P.
Antibody Properties Associate with Clinical Phenotype in LGI1 Encephalitis.
Cells. 2023 Jan 11;12(2):282.
Lücke E, Schraven B, Borucki K, Lux A, Reinhold D, Wu Q, Schreiber J.
Patterns of allergic sensitization in adults with severe asthma: the ATLAS non-interventional study.
J Asthma. 2023 May 31:1-9.
Massacci G, Venafra V, Latini S, Bica V, Pugliese GM, Graziosi S, Klingelhuber F, Krahmer N, Fischer T, Mougiakakos D, Boettcher M, Perfetto L, Sacco F.
A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients.
Leukemia. 2023 Feb;37(2):288-297.
Mothes R, Pascual-Reguant A, Koehler R, Liebeskind J, Liebheit A, Bauherr S, Philipsen L, Dittmayer C, Laue M, von Manitius R, Elezkurtaj S, Durek P, Heinrich F, Heinz GA, Guerra GM, Obermayer B, Meinhardt J, Ihlow J, Radke J, Heppner FL, Enghard P, Stockmann H, Aschman T, Schneider J, Corman VM, Sander LE, Mashreghi MF, Conrad T, Hocke AC, Niesner RA, Radbruch H, Hauser AE.
Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19.
Nat Commun. 2023 Feb 11;14(1):791.
Pugliese GM, Venafra V, Bica V, Massacci G, Latini S, Graziosi S, Fischer T, Mougiakakos D, Boettcher M, Perfetto L, Sacco F.
Impact of FLT3-ITD location on cytarabine sensitivity in AML: a network-based approach.
Leukemia. 2023 May;37(5):1151-1155.
Raschick M, Richter A, Fischer L, Knopf L, Schult A, Yakupov R, Behnisch G, Guttek K, Düzel E, Dunay IR, Seidenbecher CI, Schraven B, Reinhold D, Schott BH.
Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults.
J Neural Transm (Vienna). 2023 Apr 28.
Reimann AM, Schalk E, Jost F, Mougiakakos D, Weber D, Döhner H, Récher C, Dumas PY, Ditzhaus M, Fischer T, Sager S.
AML consolidation therapy: timing matters.
J Cancer Res Clin Oncol. 2023 Nov;149(15):13811-13821.
Reinhold D, Farztdinov V, Yan Y, Meisel C, Sadlowski H, Kühn J, Perschel FH, Endres M, Düzel E, Vielhaber S, Guttek K, Goihl A, Venø M, Teegen B, Stöcker W, Stubbemann P, Kurth F, Sander LE, Ralser M, Otto C, Streit S, Jarius S, Ruprecht K, Radbruch H, Kjems J, Mülleder M, Heppner F, Körtvelyessy P.
The brain reacting to COVID-19: analysis of the cerebrospinal fluid proteome, RNA and inflammation.
J Neuroinflammation. 2023 Feb 9;20(1):30.
Reinhold D, Reinhold A, Schraven B, Feist E.
[General knowledge of frequently applied test procedures in rheumatological and immunological diagnostics and research].
Z Rheumatol. 2023 Mar 3:1–6. German.
Roder M#, Franz T#, Negele J#, Schreiber J*, Kahlfuss S*.
Asthma bronchiale - Unterschiedliche Endotypen, unterschiedliche Therapien.
Deutsches Ärzteblatt. 2023. Dtsch Arztebl 2023; 120(15): [18]. *Corr. authors #First-authors
Roggenbuck D, Goihl A, Sowa M, Lopens S, Rödiger S, Schierack P, Conrad K, Sommer U, Jöhrens K, Grützmann R, Reinhold D, Laass MW.
Human glycoprotein-2 expressed in Brunner glands - A putative autoimmune target and link between Crohn's and coeliac disease.
Clin Immunol. 2023 Jan 4;247:109214.
Volkmar K, Jaedtka M, Baars I, Walber B, Philipp MS, Bagola K, Müller AJ, Heine H, van Zandbergen G.
Investigating pyroptosis as a mechanism of L. major cell-to-cell spread in the human BLaER1 infection model.
Mol Microbiol. 2023 Aug 23.