INSTITUT FÜR MOLEKULARE UND KLINISCHE IMMUNOLOGIE

Publikationen 2014

Harder T, Guttek K, Philipsen L, Simeoni L, Schraven B, Reinhold D.
Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation.
Cell Commun Signal. 2014 Dec 8;12(1):74. doi: 10.1186/s12964-014-0074-6.

Simma N, Bose T, Kahlfuß S, Mankiewicz J, Lowinus T, Lühder F, Schüler T, Schraven B, Heine M, Bommhardt U.
NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells.
Cell Commun Signal. 2014 Dec 5;12(1):75. 

Schubert C, Guttek K, Grüngreiff K, Thielitz A, Bühling F, Reinhold A, Brocke S, Reinhold D.
Oral zinc aspartate treats experimental autoimmune encephalomyelitis.
Biometals. 2014 Dec;27(6):1249-62. doi: 10.1007/s10534-014-9786-8. Epub 2014 Aug 22.

Roggenbuck D, Vermeire S, Hoffman I, Reinhold D, Schierack P, Goihl A, von Arnim U, De Hertogh G, Polymeros D, Bogdanos DP, Bossuyt X.
Evidence of Crohn's disease-related anti-glycoprotein 2 antibodies in patients with celiac disease.
Clin Chem Lab Med. 2014 Nov 20. pii: /j/cclm.ahead-of-print/cclm-2014-0238/cclm-2014-0238.xml. doi: 10.1515/cclm-2014-0238. [Epub ahead of print]

Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E, Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D.
Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.
PLoS One. 2014 Sep 16;9(9):e107743. doi: 10.1371/journal.pone.0107743. eCollection 2014.

Drynda A1, Singh G, Buchhorn GH, Awiszus F, Ruetschi M, Feuerstein B, Kliche S, Lohmann CH.
Metallic wear debris may regulate CXCR4 expression in vitro and in vivo.
J Biomed Mater Res A. 2014 Sep 10. doi: 10.1002/jbm.a.35330. [Epub ahead of print]

Belikov AV, Schraven B, Simeoni L.
TCR-triggered extracellular superoxide production is not required for T-cell activation.
Cell Commun Signal. 2014 Aug 1;12:50. doi: 10.1186/s12964-014-0050-1.

Schierack P, Rödiger S, Kolenda R, Hiemann R, Berger E, Grzymajło K, Swidsinski A, Juretzek T, Meissner D, Mydlak K, Reinhold D, Nolan LK, Roggenbuck D.
Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2).
Gut. 2014 Jul 29. pii: gutjnl-2014-307854. doi: 10.1136/gutjnl-2014-307854. [Epub ahead of print]

Prokazov Y, Turbin E, Weber A, Hartig R, Zuschratter W.
Position sensitive detector for fluorescence lifetime imaging.

JINST 2014 105P_0914 doi:10.1088/1748-0221/9/12/C12015

Nass N, Brömme HJ, Hartig R, Korkmaz S, Sel S, Hirche F, Ward A, Simm A, Wiemann S, Lykkesfeldt AE, Roessner A, Kalinski T.
Differential Response to α-Axoaldehydes in Tamoxifen Resistant MCF-7 Breast Cancer Cells.
PLoS One. 2014 Jul 1;9(7):e101473.

Busse S, Steiner J, Micheel J, Dobrowolny H, Mawrin C, Krause TJ, Adamaszek M, Bogerts B, Bommhardt U, Hartig R, Busse M.
Age-related increase of VGF-expression in T lymphocytes.
Aging (Albany NY). 2014 Jun;6(6):440-53.

Lettau M, Kliche S, Kabelitz D, Janssen O.
The adapter proteins ADAP and Nck cooperate in T cell adhesion.
Mol Immunol. 2014 Jul;60(1):72-9. doi: 10.1016/j.molimm.2014.03.017. Epub 2014 Apr 24.

Fiedler A, Grecksch G, Reinhold A, Schraven B, Becker A.
Hippocampus-dependent learning in SKAP-HOM deficient mice.
Behav Brain Res. 2014 May 9;270C:125-130. doi: 10.1016/j.bbr.2014.04.051. [Epub ahead of print]

Poltorak M, Meinert I, Stone JC, Schraven B, Simeoni L.
Sos1 regulates sustained TCR-mediated Erk activation.
Eur J Immunol. 2014 May;44(5):1535-40. doi: 10.1002/eji.201344046. Epub 2014 Feb 20.

Roggenbuck D, Reinhold D, Schierack P, Bogdanos DP, Conrad K, Laass MW.
Crohn's disease specific pancreatic antibodies: clinical and pathophysiological challenges.
Clin Chem Lab Med. 2014 Apr;52(4):483-94. doi: 10.1515/cclm-2013-0801.

Ewald F, Annemann M, Pils MC, Plaza-Sirvent C, Neff F, Erck C, Reinhold D, Schmitz I.
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice.
Cell Death Dis. 2014 Apr 10;5:e1168. doi: 10.1038/cddis.2014.138.

Herold J, Francke A, Weinert S, Schmeisser A, Hebel K, Schraven B, Roehl FW, Strasser RH, Braun-Dullaeus RC.
Tetanus toxoid-pulsed monocyte vaccination for augmentation of collateral vessel growth.
J Am Heart Assoc. 2014 Apr 14;3(2):e000611.

Rehberg K, Kliche S, Madencioglu DA, Thiere M, Müller B, Meineke BM, Freund C, Budinger E, Stork O.
The serine/threonine kinase ndr2 controls integrin trafficking and integrin-dependent neurite growth.
J Neurosci. 2014 Apr 9;34(15):5342-54.

Olekhnovitch R, Ryffel B, Müller AJ, Bousso P.
Collective nitric oxide production provides tissue-wide immunity during Leishmania infection.
J Clin Invest. 2014 Apr 1;124(4):1711-22. doi: 10.1172/JCI72058. Epub 2014 Mar 10.

Wolleschak D, Mack TS, Perner F, Frey S, Schnoeder TM, Wagner MC, Höding C, Pils MC, Parkner A, Kliche S, Schraven B, Hebel K, Brunner-Weinzierl M, Ranjan S, Isermann B, Lipka DB, Fischer T, Heidel FH.
Clinically relevant doses of FLT3-kinase inhibitors Quizartinib and Midostaurin do not impair T-cell reactivity and function.
Haematologica. 2014 Mar 14. [Epub ahead of print]

Wex T, Grungreiff K, Schutte K, Stengritt M, Reinhold D.
Expression analysis of zinc transporters in resting and stimulated human peripheral blood mononuclear cells.
Biomed Rep. 2014 Mar;2(2):217-222. Epub 2014 Jan 13.

Kahlfuß S, Simma N, Mankiewicz J, Bose T, Lowinus T, Klein-Hessling S, Sprengel R, Schraven B, Heine M, Bommhardt U.
Immunosuppression by N-Methyl-D-Aspartate Receptor Antagonists Is Mediated through Inhibition of Kv1.3 and KCa3.1 Channels in T Cells.
Mol Cell Biol. 2014 Mar;34(5):820-31. doi: 10.1128/MCB.01273-13. Epub 2013 Dec 16.

Reinhold D, Brocke S.
DPP4-directed therapeutic strategies for MERS-CoV.
Lancet Infect Dis. 2014 Feb;14(2):100-1. doi: 10.1016/S1473-3099(13)70696-0.

Schreiber L, Pietzsch B, Floess S, Farah C, Jänsch L, Schmitz I, Huehn J.
The Treg-Specific Demethylated Region Stabilizes Foxp3 Expression Independently of NF-κB Signaling.
PLoS One. 2014 Feb 5;9(2):e88318. doi: 10.1371/journal.pone.0088318. eCollection 2014.

Roggenbuck D, Hiemann R, Schierack P, Reinhold D, Conrad K.
Digital immunofluorescence enables automated detection of antinuclear antibody endpoint titers avoiding serial dilution.
Clin Chem Lab Med. 2014 Feb;52(2):e9-11. doi: 10.1515/cclm-2013-0543.

Schmerse F, Woidacki K, Riek-Burchardt M, Reichardt P, Roers A, Tadokoro CE, Zenclussen AC.
In vivo visualization of uterine mast cells by 2-photon microscopy.
Reproduction. 2014 Feb 17. [Epub ahead of print]

Mobashir M, Madhusudhan T, Isermann B, Beyer T, Schraven B.
Negative interactions and feedback regulations are required for transient cellular response.
Sci Rep. 2014 Jan 16;4:3718. doi: 10.1038/srep03718.

Franco R, Bortner CD, Schmitz I, Cidlowski JA.
Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.
Apoptosis. 2014 Jan;19(1):117-34. doi: 10.1007/s10495-013-0900-0.

Tammer I, Reuner J, Hartig R, Geginat G.
Induction of Candida albicans biofilm formation on silver-coated vascular grafts.
J Antimicrob Chemother. 2014 Jan 20. [Epub ahead of print] PMID: 24448486

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