INSTITUT FÜR MOLEKULARE UND KLINISCHE IMMUNOLOGIE

Publikationen 2019

Bommhardt U, Schraven B, Simeoni L.
Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy.
Int. J. Mol. Sci. 2019, 20(14), 3500

Busse M, Campe KJ, Nowak D, Schumacher A, Plenagl S, Langwisch S, Tiegs G, Reinhold A, Zenclussen AC.
IL-10 producing B cells rescue mouse fetuses from inflammation-driven fetal death and are able to modulate T cell immune responses.
Sci Rep. 2019 Jun 27;9(1):9335. doi: 10.1038/s41598-019-45860-2

Comito G, Iscaro A, Bacci M, Morandi A, Ippolito L, Parri M1, Montagnani I, Raspollini MR, Serni S, Simeoni L, Giannoni E, Chiarugi P.
Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis.
Oncogene. 2019 May;38(19):3681-3695. doi: 10.1038/s41388-019-0688-7. Epub 2019 Jan 21.

Cossarizza A, et.al.
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Eur J Immunol. 2019 Oct;49(10):1457-1973. doi: 10.1002/eji.201970107.

De Bortoli F, Neumann A, Kotte A, Timmermann B, Schüler T, Wahl MC, Loll B, Heyd F.
Increased versatility despite reduced molecular complexity: evolution, structure and function of metazoan splicing factor PRPF39.
Nucleic Acids Res. 2019 Apr 5. pii: gkz243. doi: 10.1093/nar/gkz243  [Epub ahead of print]

Dudeck J, Froebel J, Kotrba J, Lehmann CHK, Dudziak D, Speier S, Nedospasov SA, Schraven B, Dudeck A.
Engulfment of mast cell secretory granules on skin inflammation boosts dendritic cell migration and priming efficiency.
J Allergy Clin Immunol. 2019 May;143(5):1849-1864.e4.

Düsedau HP, Kleveman J, Figueiredo CA, Biswas A, Steffen J, Kliche S, Haak S, Zagrebelsky M, Korte M, Dunay IR.
p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation.
Glia. 2019 Jan;67(1):193-211.

French T, Düsedau HP, Steffen J, Biswas A, Ahmed N, Hartmann S, Schüler T, Schott BH, Dunay IR.
Neuronal impairment following chronic Toxoplasma gondii infection is aggravated by intestinal nematode challenge in an IFN-γ-dependent manner.
J Neuroinflammation. 2019 Jul 29;16(1):159. doi: 10.1186/s12974-019-1539-8.

Frentzel S, Katsoulis-Dimitriou K, Jeron A, Schmitz I, Bruder D.
Essential role of IκBNS for in vivo CD4+ T cell activation, proliferation and Th1 cell differentiation during Listeria monocytogenes infection in mice.
Eur J Immunol. 2019 May 3. doi: 10.1002/eji.201847961. [Epub ahead of print]

Handschuh J, Amore J, Müller AJ.
From the Cradle to the Grave of an Infection: Host-Pathogen Interaction Visualized by Intravital Microscopy.
Cytometry A. 2019 Nov 27. doi: 10.1002/cyto.a.23938. [Epub ahead of print] Review.

Knop L, Frommer C, Stoycheva D, Dieser K, Kalinke U, Blankenstein T, Kammertoens T, Dunay IR, Schüler T.
Interferon-γ Receptor Signaling in Dendritic Cells Restrains Spontaneous Proliferation of CD4+ T Cells in Chronic Lymphopenic Mice.
Front. Immunol., 07 February 2019 | https://doi.org/10.3389/fimmu.2019.00140.

Lowinus T, Heidel FH, Bose T, Nimmagadda SC, Schnöder T, Cammann C, Schmitz I, Seifert U, Fischer T, Schraven B, Bommhardt U.
Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling.
Cell Commun Signal. 2019 Jan 16;17(1):5.

Luebke T, Schwarz L, Beer YY, Schumann S, Misterek M, Sander FE, Plaza-Sirvent C, Schmitz I.
c-FLIP and CD95 signaling are essential for survival of renal cell carcinoma.
Cell Death Dis. 2019 May 16;10(6):384. doi: 10.1038/s41419-019-1609-y

Schuster M*, Plaza-Sirvent C*, Visekruna, A Huehn J, Schmitz I.
Generation of Foxp3+CD25− Regulatory T-Cell Precursors Requires c-Rel and IκBNS.
Front. Immunol., 10 July 2019 doi: 10.3389/fimmu.2019.01583
* These authors have contributed equally to this work

Seiß EA, Krone A, Formaglio P, Goldmann O, Engelmann S, Schraven B, Medina E, Müller AJ.
Longitudinal proliferation mapping in vivo reveals NADPH oxidase-mediated dampening of Staphylococcus aureus growth rates within neutrophils.
Sci Rep. 2019 Apr 5;9(1):5703. doi: 10.1038/s41598-019-42129-6.

Rudolph J, Meinke C, Voss M, Guttek K, Kliche S, Reinhold D, Schraven B, Reinhold A.
Immune Cell-Type Specific Ablation of Adapter Protein ADAP Differentially Modulates EAE.
Front Immunol. 2019 Oct 1;10:2343. doi: 10.3389/fimmu.2019.02343. eCollection 2019.

Rudolph JM, Guttek K, Weitz G, Meinke CA, Kliche S, Reinhold D, Schraven B, Reinhold A.
Characterization of mice with a platelet-specific deletion of the adapter molecule ADAP.
Mol Cell Biol. 2019 Mar 4. pii: MCB.00365-18. doi: 10.1128/MCB.00365-18 . [Epub ahead of print]

Vo DH, Hartig R, Weinert S, Haybaeck J, Nass N.
G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells.
Biomolecules. 2019 Sep 18;9(9). pii: E503. doi: 10.3390/biom9090503.

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