INSTITUT FÜR MOLEKULARE UND KLINISCHE IMMUNOLOGIE

Publikationen 2021

Baars I, Lokau J, Sauerland I, Müller AJ, Garbers C.
Interleukin-11 receptor expression on monocytes is dispensable for their recruitment and pathogen uptake during Leishmania major infection.
Cytokine. 2021 Dec;148:155699. doi: 10.1016/j.cyto.2021.155699.

Böning MAL, Parzmair GP, Jeron A, Düsedau HP, Kershaw O, Xu B, Relja B, Schlüter D, Dunay IR, Reinhold A, Schraven B, Bruder D.
Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function.
Front Immunol. 2021 Sep 30;12:724855. doi: 10.3389/fimmu.2021.724855. eCollection 2021. PMID: 346592

Busse M, Plenagl S, Campe NKJ, Müller AJ, Tedford K, Schumacher A, Zenclussen AC.
Maternal B Cell-Intrinsic MyD88 Signaling Mediates LPS-Driven Intrauterine Fetal Death.
Cells. 2021 Oct 8;10(10):2693. doi: 10.3390/cells10102693.

Dadwal N, Mix C, Reinhold A, Witte A, Freund C, Schraven B, Kliche S.
The Multiple Roles of the Cytosolic Adapter Proteins ADAP, SKAP1 and SKAP2 for TCR/CD3 -Mediated Signaling Events.
Front Immunol. 2021 Jul 6;12:703534. doi: 10.3389/fimmu.2021.703534.

Dudeck J, Kotrba J, Immler R, Hoffmann A, Voss M, Alexaki VI, Morton L, Jahn SR, Katsoulis-Dimitriou K, Winzer S, Kollias G, Fischer T, Nedospasov SA, Dunay IR, Chavakis T, Müller AJ, Schraven B, Sperandio M, Dudeck A.
Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation.
Immunity. 2021 Jan 15:S1074-7613(20)30545-8. doi: 10.1016/j.immuni.2020.12.017.

Formaglio P, Alabdullah M, Siokis A, Handschuh J, Sauerland I, Fu Y, Krone A, Gintschel P, Stettin J, Heyde S, Mohr J, Philipsen L, Schröder A, Robert PA, Zhao G, Khailaie S, Dudeck A, Bertrand J, Späth GF, Kahlfuß S, Bousso P, Schraven B, Huehn J, Binder S, Meyer-Hermann M, Müller AJ.
Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells.
Immunity. 2021 Oct 15:S1074-7613(21)00406-4. doi: 10.1016/j.immuni.2021.09.021. Online ahead of print.

French T, Israel N, Düsedau HP, Tersteegen A, Steffen J, Cammann C, Topfstedt E, Dieterich D, Schüler T, Seifert U, Dunay IR.
The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis.
Front Immunol. 2021 Apr 21;12:619465. doi: 10.3389/fimmu.2021.619465. eCollection 20

Grüngreiff K, Gottstein T, Reinhold D, Blindauer CA.
Albumin Substitution in Decompensated Liver Cirrhosis: Don't Forget Zinc.
Nutrients. 2021 Nov 10;13(11):4011. doi: 10.3390/nu13114011.

Hartl FA, Ngoenkam J, Beck-Garcia E, Cerqueira L, Wipa P, Paensuwan P, Suriyaphol P, Mishra P, Schraven B, Günther S, Pongcharoen S, Schamel WWA, Minguet S.
Cooperative Interaction of Nck and Lck Orchestrates Optimal TCR Signaling.
Cells. 2021 Apr 7;10(4):834. doi: 10.3390/cells10040834.

Janicova A, Becker N, Xu B, Simic M, Noack L, Wagner N, Müller AJ, Bertrand J, Marzi I, Relja B.
Severe Traumatic Injury Induces Phenotypic and Functional Changes of Neutrophils and Monocytes.
J Clin Med. 2021 Sep 14;10(18):4139. doi: 10.3390/jcm10184139.

Jordan PM, Andreas N, Groth M, Wegner P, Weber F, Jäger U, Küchler C, Werz O, Serfling E, Kamradt T, Dudeck A, Drube S.
ATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoids.
Immunology. 2021 Nov;164(3):541-554. doi: 10.1111/imm.13386. Epub 2021 Jun 30.

Kleinholz CL, Riek-Burchardt M, Seiß EA, Amore J, Gintschel P, Philipsen L, Bousso P, Relja B, Schraven B, Handschuh J, Mohr J, Müller AJ.
Ly6G deficiency alters the dynamics of neutrophil recruitment and pathogen capture during Leishmania major skin infection.
Sci Rep. 2021 Jul 23;11(1):15071. doi: 10.1038/s41598-021-94425-9.

Lingel H, Meltendorf S, Billing U, Thurm C, Vogel K, Majer C, Prätsch F, Roggenbuck D, Heuft HG, Hachenberg T, Feist E, Reinhold D, Brunner-Weinzierl MC.
Unique autoantibody prevalence in long-term recovered SARS-CoV-2-infected individuals.
J Autoimmun. 2021 Aug;122:102682. doi: 10.1016/j.jaut.2021.102682. Epub 2021 Jun 21.

Luecke E, Jeron A, Kroeger A, Bruder D, Stegemann-Koniszewski S, Jechorek D, Borucki K, Reinhold D, Reinhold A, Foellner S, Walles T, Hachenberg T, Schreiber J.
Eosinophilic pulmonary vasculitis as a manifestation of the hyperinflammatory phase of COVID-19.
J Allergy Clin Immunol. 2021 Jan;147(1):112-113. doi: 10.1016/j.jaci.2020.09.026. Epub 2020 Oct 26.

Meinhardt J, Radke J, Dittmayer C, Franz J, Thomas C, Mothes R, Laue M, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, Conrad C, Eils R, Stenzel W, Windgassen M, Rößler L, Goebel HH, Gelderblom HR, Martin H, Nitsche A, Schulz-Schaeffer WJ, Hakroush S, Winkler MS, Tampe B, Scheibe F, Körtvélyessy P, Reinhold D, Siegmund B, Kühl AA, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Ingold-Heppner B, Stadelmann C, Drosten C, Corman VM, Radbruch H, Heppner FL.
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
Nat Neurosci. 2021 Feb;24(2):168-175. doi: 10.1038/s41593-020-00758-5.

Meinshausen AK, Herbster M, Zwahr C, Soldera M, Müller A, Halle T, Lasagni AF, Bertrand J.
Aspect ratio of nano/microstructures determines Staphylococcus aureus adhesion on PET and titanium surfaces.
J Appl Microbiol. 2021 Sep;131(3):1498-1514. doi: 10.1111/jam.15033.

Mougiakakos D, Kahlfuss S.
"Moonlighting" at the power plant: how mitochondria facilitate serial killing by CD8+ cytotoxic T cells.
Signal Transduct Target Ther. 2021 Dec 22;6(1):436. doi: 10.1038/s41392-021-00846-3. IF: 18.187

Pascual-Reguant A, Köhler R, Mothes R, Bauherr S, Hernández DC, Uecker R, Holzwarth K, Kotsch K, Seidl M, Philipsen L, Müller W, Romagnani C, Niesner R, Hauser AE.
Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells.
Nat Commun. 2021 Mar 19;12(1):1737. doi: 10.1038/s41467-021-21994-8.

Prado Acosta M, Goyette-Desjardins G, Scheffel J, Dudeck A, Ruland J, Lepenies B.
S-Layer From Lactobacillus brevis Modulates Antigen-Presenting Cell Functions via the Mincle-Syk-Card9 Axis.
Front Immunol. 2021 Mar 1;12:602067. doi: 10.3389/fimmu.2021.602067.

Reddig A, Voss L, Guttek K, Roggenbuck D, Feist E, Reinhold D.
Impact of Different JAK Inhibitors and Methotrexate on Lymphocyte Proliferation and DNA Damage.
J Clin Med. 2021 Apr 1;10(7):1431. doi: 10.3390/jcm10071431.

Reinhold D, Brocke S.
The differential roles of zinc in immune responses and their potential implications in antiviral immunity against SARS-CoV-2.
Clin Nutr. 2021 Feb;40(2):652. doi: 10.1016/j.clnu.2020.12.005. Epub 2020 Dec 10.

Reinhold D, Guttek K, Reddig A, Voss L, Schubert C, Kahlfuss S, Grüngreiff K, Schraven B, Reinhold A.
Zinc Aspartate Induces IL-16 Secretion and Apoptosis in Human T Cells.
Biomedicines. 2021 Mar 1;9(3):246. doi: 10.3390/biomedicines9030246.

Schreiber S, Hammers CM, Kaasch AJ, Schraven B, Dudeck A, Kahlfuss S.
Metabolic Interdependency of Th2 Cell-Mediated Type 2 Immunity and the Tumor Microenvironment.
Frontiers in Immunology. 2021 May 31;12:632581. doi: 10.3389/fimmu.2021.632581. eCollection 2021.

Thurm C, Schraven B, Kahlfuss S.
ABC Transporters in T Cell-Mediated Physiological and Pathological Immune Responses.
Int J Mol Sci. 2021 Aug 25;22(17):9186. doi: 10.3390/ijms22179186.

Tripathi K, Demiray YE, Kliche S, Jing L, Hazra S, Hazra JD, Richter-Levin G, Stork O.
Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits.
Neurobiol Stress. 2021 Jun 2;15:100350. doi: 10.1016/j.ynstr.2021.100350.

Voss L, Guttek K, Reddig A, Reinhold A, Voss M, Simeoni L, Schraven B, Reinhold D.
Pitavastatin Is a Highly Potent Inhibitor of T-Cell Proliferation.
Pharmaceuticals (Basel). 2021 Jul 27;14(8):727. doi: 10.3390/ph14080727

Voss L, Guttek K, Reddig A, Reinhold A, Voss M, Schraven B, Reinhold D.
Screening of FDA-Approved Drug Library Identifies Adefovir Dipivoxil as Highly Potent Inhibitor of T Cell Proliferation.
Front Immunol. 2021 Jan 8;11:616570. doi: 10.3389/fimmu.2020.616570. eCollection 2020.

Voss M, Kotrba J, Gaffal E, Katsoulis-Dimitriou K, Dudeck A.
Mast Cells in the Skin: Defenders of Integrity or Offenders in Inflammation?
Int J Mol Sci. 2021 Apr 27;22(9):4589. doi: 10.3390/ijms22094589.

Wunsch E, Norman GL, Milkiewicz M, Krawczyk M, Bentow C, Shums Z, Mahler M, Lopens S, Reinhold D, Franke A, Schramm C, Roggenbuck D, Milkiewicz P.
Anti-glycoprotein 2 (anti-GP2) IgA and anti-neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3-ANCA): antibodies to predict severe disease, poor survival and cholangiocarcinoma in primary sclerosing cholangitis.
Aliment Pharmacol Ther. 2021 Jan;53(2):302-313. doi: 10.1111/apt.16153. Epub 2020 Nov 7.

Letzte Änderung: 05.10.2022 - Ansprechpartner:

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