INSTITUT FÜR MOLEKULARE UND KLINISCHE IMMUNOLOGIE

Publikationen 2012

Thielitz A, Bellutti M, Bonnekoh B, Franke I, Wiede A, Lotzing M, Reinhold D, Gollnick H.
Progressive lipo-lymphedema associated with increased activity of dermal fibroblasts in monoclonal gammopathy of undetermined significance: is there a causal relationship?
Lymphology. 2012 Sep;45(3):124-9.

Mobashir M, Schraven B, Beyer T.
Simulated evolution of signal transduction networks.
PLoS One. 2012;7(12):e50905.

Amelie Witte, Janine Degen, Kathleen Baumgart, Natalie Waldt, Benno Kuropka, Christian Freund, Burkhart Schraven, and Stefanie Kliche
Emerging Roles of ADAP, SKAP55, and SKAP-HOM for Integrin and NF-κB Signaling in T cells
Clinical & Cellular Immunology 2012, S12

Bogdanos DP, Roggenbuck D, Reinhold D, Wex T, Pavlidis P, von Arnim U, Malfertheiner P, Forbes A, Conrad K, Laass MW.
Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn's disease.
BMC Gastroenterol. 2012 Aug 6;12:102.

Werner L, Paclik D, Fritz C, Reinhold D, Roggenbuck D, Sturm A.
Identification of pancreatic glycoprotein 2 as an endogenous immunomodulator of innate and adaptive immune responses.
J Immunol. 2012 Sep 15;189(6):2774-83. doi: 10.4049/jimmunol.1103190. Epub 2012 Aug 13.

Guerrero AD, Ingo Schmitz, Min Chen and Jin Wang
Promotion of Caspase Activation by Caspase-9-mediated Feedback Amplification of Mitochondrial Damage
J Clin Cell Immunol 2012, 3:3

Urban S, Textoris-Taube K, Reimann B, Janek K, Dannenberg T, Ebstein F, Seifert C, Zhao F, Kessler JH, Halenius A, Henklein P, Paschke J, Cadel S, Bernhard H, Ossendorp F, Foulon T, Schadendorf D, Paschen A, Seifert U.
The efficiency of human cytomegalovirus pp65(495-503) CD8+ T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidases.
J Immunol. 2012 Jul 15;189(2):529-38. Epub 2012 Jun 15.

Ebstein F, Kloetzel PM, Krüger E, Seifert U.
Emerging roles of immunoproteasomes beyond MHC class I antigen processing.
Cell Mol Life Sci. 2012 Aug;69(15):2543-58. Epub 2012 Mar 2. Review.

Hansen W, Hutzler M, Abel S, Alter C, Stockmann C, Kliche S, Albert J, Sparwasser T, Sakaguchi S, Westendorf AM, Schadendorf D, Buer J, Helfrich I.
Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth.
J Exp Med. 2012 Oct 22;209(11):2001-16.

Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.

Keil E, Höcker R, Schuster M, Essmann F, Ueffing N, Hoffman B, Liebermann DA, Pfeffer K, Schulze-Osthoff K, Schmitz I.
Cell Death Differ. 2012 Oct 12. doi: 10.1038/cdd.2012.129. [Epub ahead of print]

Constitutive Akt1 signals attenuate B-cell receptor signaling and proliferation, but enhance B-cell migration and effector function.
Pierau M, Na SY, Simma N, Lowinus T, Marx A, Schraven B, Bommhardt UH.
Eur J Immunol. 2012 Aug 28. doi: 10.1002/eji.201242397. [Epub ahead of print]

Shalapour S, Deiser K, Kühl AA, Glauben R, Krug SM, Fischer A, Sercan O, Chappaz S, Bereswill S, Heimesaat MM, Loddenkemper C, Fromm M, Finke D, Hämmerling GJ, Arnold B, Siegmund B, Schüler T.
Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis.
PLoS One. 2012;7(2):e31939. Epub 2012 Feb 27.

König S, Probst-Kepper M, Reinl T, Jeron A, Huehn J, Schraven B, Jänsch L.
First insight into the kinome of human regulatory T cells.
PLoS One. 2012;7(7):e40896. Epub 2012 Jul 16.

Warnecke N, Poltorak M, Kowtharapu BS, Arndt B, Stone JC, Schraven B, Simeoni L.
TCR-mediated Erk activation does not depend on Sos and Grb2 in peripheral human T cells.
EMBO Rep. 2012 Apr;13(4):386-91.

Togni M, Engelmann S, Reinhold D, Schraven B, Reinhold A.
The adapter protein ADAP is required for selected dendritic cell functions.
Cell Commun Signal. 2012 Jun 6;10(1):14.

Röhnert P, Schmidt W, Emmerlich P, Goihl A, Wrenger S, Bank U, Nordhoff K, Täger M, Ansorge S, Reinhold D, Striggow F.
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.
J Neuroinflammation. 2012 Feb 28;9:44.

Stoye D, Schubert C, Goihl A, Guttek K, Reinhold A, Brocke S, Grüngreiff K, Reinhold D.
Zinc aspartate suppresses T cell activation in vitro and relapsing experimental autoimmune encephalomyelitis in SJL/J mice.
Biometals. 2012 Jun;25(3):529-39. Epub 2012 Feb 19.

Lapp T, Reinhold D, Maier P, Reinhard T.
[Old immune system - New information? : Importance of mononuclear phagocytes in corneal allograft rejection.]
Ophthalmologe. 2012 Apr 13. [Epub ahead of print] German.

 Conrad K, Roggenbuck D, Ittenson A, Reinhold D, Buettner T, Laass MW.
A new dot immunoassay for simultaneous detection of celiac specific antibodies and IgA-deficiency.
Clin Chem Lab Med. 2012 Feb;50(2):337-43. doi: 10.1515/cclm.2011.760.

Andrae N, Kirches E, Hartig R, Haase D, Keilhoff G, Kalinski T, Mawrin C.
Sunitinib targets PDGF-receptor and Flt3 and reduces survival and migration of human meningioma cells.
Eur J Cancer. 2012 Mar 3. [Epub ahead of print]

Helena Block, Jan M. Herter, Jan Rossaint, Anika Stadtmann, Stefanie Kliche, Clifford A. Lowell,and Alexander Zarbock.
Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury.
J. Exp. Med. Vol. 2012; 209 No. 2 407-421

Goihl A, Rolle AM, Kähne T, Reinhold A, Wrenger S, Reinhold D.
Methodologic issues in the measurement of interleukin-16 in clinical blood samples using immunoassays.
Cytokine. 2012 Apr;58(1):1-5. Epub 2012 Jan 11.

RM Linka, SL Risse, K Bienemann, M Werner, Y Linka, F Krux, C Synaeve, R Deenen, S Ginzel, R Dvorsky, M Gombert, A Halenius8, R Hartig,
M Helminen, A Fischer, P Stepensky, K Vettenranta, K Kohrer, MR Ahmadian, H-J Laws, B Fleckenstein1, H Jumaa, S Latour, B Schraven and A Borkhardt
Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases
Leukemia 2012 Jan 6. doi: 10.1038/leu.2011.371. [Epub ahead of print]

Schmidt A, Oberle N, Weiss EM, Vobis D, Frischbutter S, Baumgrass R, Falk CS, Haag M, Brügger B, Lin H, Mayr GW, Reichardt P, Gunzer M, Suri-Payer E, Krammer PH.
Human regulatory T cells rapidly suppress T cel receptor-induced Ca2+s, NF-κB and NFAT signaling in conventional T cells
Science Signaling 2011 Dec 20;4(204):ra90.

Kliche S*, Worbs T, Wang X, Degen J, Patzak I, Meineke B, Togni M, Moser M, Reinhold A, Kiefer F, Freund C, Förster R, Schraven B.
CCR7-mediated LFA-1 functions in T cells are regulated by two independent ADAP/SKAP55-modules.
Blood. 2012;119(3):777-785
  * corresponding author

Bajbouj K, Mawrin C, Hartig R, Schulze-Luehrmann J, Wilisch-Neumann A, Roessner A, Schneider-Stock R.
P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.
J Neurooncol. 2012 Jan 20.

Conrad K, Roggenbuck D, Reinhold D, Sack U.
Autoantibody diagnostics in clinical practice.
Autoimmun Rev. 2012 Jan;11(3):207-11. Epub 2011 May 18.

Wienecke J, Hebel K, Hegel KJ, Pierau M, Brune T, Reinhold D, Pethe A, Brunner-Weinzierl MC.
Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus.
Placenta. 2012 Jan;33(1):39-46. Epub 2011 Nov 16.

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