Publications (since 2010)
2024
Goihl A, Reinhold D, Reinhold A, Schraven B, Körtvelyessy P.
Leucine-Rich Glioma-Inactivated 1 (LGI1) Protein Stimulates Proliferation and IL-10 Production in Peripheral Blood Mononuclear Cells of Patients with LGI1 Antibody-Mediated Autoimmune Encephalitis In Vitro.
Int J Mol Sci. 2024 Feb 23;25(5):2581.
Grüngreiff K, Reinhold D, Maret W.
Why a pinch of zinc in liver disease matters.
Ann Hepatol. 2024 Jan-Feb;29(1):101152.
Radke J, Meinhardt J, Aschman T, Chua RL, Farztdinov V, Lukassen S, Ten FW, Friebel E, Ishaque N, Franz J, Huhle VH, Mothes R, Peters K, Thomas C, Schneeberger S, Schumann E, Kawelke L, Jünger J, Horst V, Streit S, von Manitius R, Körtvélyessy P, Vielhaber S, Reinhold D, Hauser AE, Osterloh A, Enghard P, Ihlow J, Elezkurtaj S, Horst D, Kurth F, Müller MA, Gassen NC, Melchert J, Jechow K, Timmermann B, Fernandez-Zapata C, Böttcher C, Stenzel W, Krüger E, Landthaler M, Wyler E, Corman V, Stadelmann C, Ralser M, Eils R, Heppner FL, Mülleder M, Conrad C, Radbruch H.
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Nat Neurosci. 2024 Mar;27(3):409-420.
Zou M, Pezoldt J, Mohr J, Philipsen L, Leufgen A, Cerovic V, Wiechers C, Pils M, Ortiz D, Hao L, Yang J, Beckstette M, Dupont A, Hornef M, Dersch P, Strowig T, Müller AJ, Raila J, Huehn J.
Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes.
Cell Rep. 2024 Apr 29;43(5):114153. doi: 10.1016/j.celrep.2024.114153. Online ahead of print. PMID: 38687643
2023
Guttek K, Reinhold A, Grüngreiff K, Schraven B, Reinhold D.
Zinc aspartate induces proliferation of resting and antigen-stimulated human PBMC under high-density cell culture condition.
J Trace Elem Med Biol. 2023 Mar 11;77:127152.
Ludewig S, Salzburger L, Goihl A, Rohne J, Leypoldt F, Bittner D, Düzel E, Schraven B, Reinhold D, Korte M, Körtvélyessy P.
Antibody Properties Associate with Clinical Phenotype in LGI1 Encephalitis.
Cells. 2023 Jan 11;12(2):282.
Lücke E, Schraven B, Borucki K, Lux A, Reinhold D, Wu Q, Schreiber J.
Patterns of allergic sensitization in adults with severe asthma: the ATLAS non-interventional study.
J Asthma. 2023 May 31:1-9.
Raschick M, Richter A, Fischer L, Knopf L, Schult A, Yakupov R, Behnisch G, Guttek K, Düzel E, Dunay IR, Seidenbecher CI, Schraven B, Reinhold D, Schott BH.
Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults.
J Neural Transm (Vienna). 2023 Apr 28.
Reinhold D, Farztdinov V, Yan Y, Meisel C, Sadlowski H, Kühn J, Perschel FH, Endres M, Düzel E, Vielhaber S, Guttek K, Goihl A, Venø M, Teegen B, Stöcker W, Stubbemann P, Kurth F, Sander LE, Ralser M, Otto C, Streit S, Jarius S, Ruprecht K, Radbruch H, Kjems J, Mülleder M, Heppner F, Körtvelyessy P.
The brain reacting to COVID-19: analysis of the cerebrospinal fluid proteome, RNA and inflammation.
J Neuroinflammation. 2023 Feb 9;20(1):30.
Reinhold D, Reinhold A, Schraven B, Feist E.
[General knowledge of frequently applied test procedures in rheumatological and immunological diagnostics and research].
Z Rheumatol. 2023 Mar 3:1–6. German.
Roggenbuck D, Goihl A, Sowa M, Lopens S, Rödiger S, Schierack P, Conrad K, Sommer U, Jöhrens K, Grützmann R, Reinhold D, Laass MW.
Human glycoprotein-2 expressed in Brunner glands - A putative autoimmune target and link between Crohn's and coeliac disease.
Clin Immunol. 2023 Jan 4;247:109214.
2022
Hammerschmidt SI, Thurm C, Bošnjak B, Bernhardt G, Reinhold A, Willenzon S, Ritter C, Reinhold D, Schraven B, Förster R.
Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination.
Eur J Immunol. 2022 Feb;52(2):356-359. doi: 10.1002/eji.202149645. Epub 2022 Jan 7.
Krone A, Fu Y, Schreiber S, Kotrba J, Borde L, Nötzold A, Thurm C, Negele J, Franz T, Stegemann-Koniszewski S, Schreiber J, Garbers C, Shukla A, Geffers R, Schraven B, Reinhold D, Dudeck A, Reinhold A, Müller AJ, Kahlfuss S.
Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc.
Sci Rep. 2022 Feb 4;12(1):1943. doi: 10.1038/s41598-022-04827-6.
Meltendorf S, Vogel K, Thurm C, Prätsch F, Reinhold A, Färber J, Heuft HG, Kaasch AJ, Hachenberg T, Weinzierl S, Schraven B, Reinhold D, Brunner-Weinzierl MC, Lingel H.
IL-13 determines specific IgE responses and SARS-CoV-2 immunity after mild COVID-19 and novel mRNA vaccination.
Eur J Immunol. 2022 Oct 22. doi: 10.1002/eji.202249951.
Thurm C, Reinhold A, Borucki K, Kahlfuss S, Feist E, Schreiber J, Reinhold D, Schraven B.
Homologous and Heterologous Anti-COVID-19 Vaccination Does Not Induce New-Onset Formation of Autoantibodies Typically Accompanying Lupus Erythematodes, Rheumatoid Arthritis, Celiac Disease and Antiphospholipid Syndrome.
Vaccines (Basel). 2022 Feb 18;10(2):333. doi: 10.3390/vaccines10020333.
2021
Grüngreiff K, Gottstein T, Reinhold D, Blindauer CA.
Albumin Substitution in Decompensated Liver Cirrhosis: Don't Forget Zinc.
Nutrients. 2021 Nov 10;13(11):4011. doi: 10.3390/nu13114011.
Lingel H, Meltendorf S, Billing U, Thurm C, Vogel K, Majer C, Prätsch F, Roggenbuck D, Heuft HG, Hachenberg T, Feist E, Reinhold D, Brunner-Weinzierl MC.
Unique autoantibody prevalence in long-term recovered SARS-CoV-2-infected individuals.
J Autoimmun. 2021 Aug;122:102682. doi: 10.1016/j.jaut.2021.102682. Epub 2021 Jun 21.
Meinhardt J, Radke J, Dittmayer C, Franz J, Thomas C, Mothes R, Laue M, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, Conrad C, Eils R, Stenzel W, Windgassen M, Rößler L, Goebel HH, Gelderblom HR, Martin H, Nitsche A, Schulz-Schaeffer WJ, Hakroush S, Winkler MS, Tampe B, Scheibe F, Körtvélyessy P, Reinhold D, Siegmund B, Kühl AA, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Ingold-Heppner B, Stadelmann C, Drosten C, Corman VM, Radbruch H, Heppner FL.
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
Nat Neurosci. 2021 Feb;24(2):168-175. doi: 10.1038/s41593-020-00758-5.
Reddig A, Voss L, Guttek K, Roggenbuck D, Feist E, Reinhold D.
Impact of Different JAK Inhibitors and Methotrexate on Lymphocyte Proliferation and DNA Damage.
J Clin Med. 2021 Apr 1;10(7):1431. doi: 10.3390/jcm10071431.
Reinhold D, Guttek K, Reddig A, Voss L, Schubert C, Kahlfuss S, Grüngreiff K, Schraven B, Reinhold A.
Zinc Aspartate Induces IL-16 Secretion and Apoptosis in Human T Cells.
Biomedicines. 2021 Mar 1;9(3):246. doi: 10.3390/biomedicines9030246.
Reinhold D, Brocke S.
The differential roles of zinc in immune responses and their potential implications in antiviral immunity against SARS-CoV-2.
Clin Nutr. 2021 Feb;40(2):652. doi: 10.1016/j.clnu.2020.12.005. Epub 2020 Dec 10.
Voss L, Guttek K, Reddig A, Reinhold A, Voss M, Simeoni L, Schraven B, Reinhold D.
Pitavastatin Is a Highly Potent Inhibitor of T-Cell Proliferation.
Pharmaceuticals (Basel). 2021 Jul 27;14(8):727. doi: 10.3390/ph14080727
Voss L, Guttek K, Reddig A, Reinhold A, Voss M, Schraven B, Reinhold D.
Screening of FDA-Approved Drug Library Identifies Adefovir Dipivoxil as Highly Potent Inhibitor of T Cell Proliferation.
Front Immunol. 2021 Jan 8;11:616570. doi: 10.3389/fimmu.2020.616570. eCollection 2020.
Wunsch E, Norman GL, Milkiewicz M, Krawczyk M, Bentow C, Shums Z, Mahler M, Lopens S, Reinhold D, Franke A, Schramm C, Roggenbuck D, Milkiewicz P.
Anti-glycoprotein 2 (anti-GP2) IgA and anti-neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3-ANCA): antibodies to predict severe disease, poor survival and cholangiocarcinoma in primary sclerosing cholangitis.
Aliment Pharmacol Ther. 2021 Jan;53(2):302-313. doi: 10.1111/apt.16153. Epub 2020 Nov 7.
2020
Grüngreiff K, Gottstein T, Reinhold D.
Zinc Deficiency-An Independent Risk Factor in the Pathogenesis of Haemorrhagic Stroke?
Nutrients. 2020 Nov 19;12(11):3548.
Körtvelyessy P, Goihl A, Guttek K, Schraven B, Prüss H, Reinhold D.
Serum and CSF cytokine levels mirror different neuroimmunological mechanisms in patients with LGI1 and Caspr2 encephalitis.
Cytokine. 2020 Nov;135:155226. doi: 10.1016/j.cyto.2020.155226. Epub 2020 Aug 12.
Körtvelyessy P, Kuhle J, Düzel E, Vielhaber S, Schmidt C, Heinius A, Leypoldt F, Schraven B, Reinhold D, Leppert D, Goihl A.
Ratio and index of Neurofilament light chain indicate its origin in Guillain-Barré Syndrome.
Ann Clin Transl Neurol. 2020 Nov;7(11):2213-2220. doi: 10.1002/acn3.51207. Epub 2020 Oct 8.
Luecke E, Jeron A, Kroeger A, Bruder D, Stegemann-Koniszewski S, Jechorek D, Borucki K, Reinhold D, Reinhold A, Foellner S, Walles T, Hachenberg T, Schreiber J.
Eosinophilic pulmonary vasculitis as a manifestation of the hyperinflammatory phase of COVID-19.
J Allergy Clin Immunol. 2020 Oct 26:S0091-6749(20)31392-0. doi: 10.1016/j.jaci.2020.09.026. Online ahead of print.
Roggenbuck D, Delmont E, Reinhold D, Schierack P, Conrad K, Boucraut J.
Autoimmune Peripheral Neuropathies and Contribution of Antiganglioside/Sulphatide Autoantibody Testing.
Mediterr J Rheumatol. 2020 Mar 31;31(1):10-18. doi: 10.31138/mjr.31.1.10. eCollection 2020 Mar.
Weise F, Vieth M, Reinhold D, Haybaeck J, Goni E, Lippert H, Ridwelski K, Lingohr P, Schildberg C, Vassos N, Kruschewski M, Krasniuk I, Grimminger PP, Waidmann O, Peitz U, Veits L, Kreuser N, Lang H, Bruns C, Moehler M, Lordick F, Gockel I, Schumacher J, Malfertheiner P, Venerito M.
Gastric cancer in autoimmune gastritis: A case-control study from the German centers of the staR project on gastric cancer research.
United European Gastroenterol J. 2020 Mar;8(2):175-184. doi: 10.1177/2050640619891580. Epub 2019 Nov 26.
Wunsch E, Norman GL, Milkiewicz M, Krawczyk M, Bentow C, Shums Z, Mahler M, Lopens S, Reinhold D, Franke A, Schramm C, Roggenbuck D, Milkiewicz P.
Anti-glycoprotein 2 (anti-GP2) IgA and anti-neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3-ANCA): antibodies to predict severe disease, poor survival and cholangiocarcinoma in primary sclerosing cholangitis.
Aliment Pharmacol Ther. 2020 Nov 7. doi: 10.1111/apt.16153. Online ahead of print.
2019
Rudolph J, Meinke C, Voss M, Guttek K, Kliche S, Reinhold D, Schraven B, Reinhold A.
Immune Cell-Type Specific Ablation of Adapter Protein ADAP Differentially Modulates EAE.
Front Immunol. 2019 Oct 1;10:2343. doi: 10.3389/fimmu.2019.02343. eCollection 2019.
Rudolph JM, Guttek K, Weitz G, Meinke CA, Kliche S, Reinhold D, Schraven B, Reinhold A.
Characterization of mice with a platelet-specific deletion of the adapter molecule ADAP.
Mol Cell Biol. 2019 Mar 4. pii: MCB.00365-18. doi: 10.1128/MCB.00365-18 . [Epub ahead of print]
2018
Friebe B, Godenschweger F, Fatahi M, Speck O, Roggenbuck D, Reinhold D, Reddig A.
The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes.
Eur Radiol Exp. 2018 Nov 28;2(1):40. doi: 10.1186/s41747-018-0069-y.
Gartmann L, Wex T, Grüngreiff K, Reinhold D, Kalinski T, Malfertheiner P, Schütte K.
Expression of zinc transporters ZIP4, ZIP14 and ZnT9 in hepatic carcinogenesis-An immunohistochemical study.
J Trace Elem Med Biol. 2018 Sep;49:35-42. doi: 10.1016/j.jtemb.2018.04.034. Epub 2018 Apr 27.
Guttek K, Wagenbrett L, Reinhold A, Grüngreiff K, Reinhold D.
Zinc aspartate suppresses proliferation and Th1/Th2/Th17 cytokine production of pre-activated human T cells in vitro.
J Trace Elem Med Biol. 2018 Sep;49:86-90. doi: 10.1016/j.jtemb.2018.05.003. Epub 2018 May 4.
Körtvelyessy P, Prüss H, Thurner L, Maetzler W, Vittore-Welliong D, Schultze-Amberger J, Heinze HJ, Reinhold D, Leypoldt F, Schreiber S, Bittner D.
Biomarkers of Neurodegeneration in Autoimmune-Mediated Encephalitis.
Front Neurol. 2018 Sep 19;9:668. doi: 10.3389/fneur.2018.00668 . eCollection 2018.
Pawlitzki M, Uebelhör J, Sweeney-Reed CM, Stephanik H, Hoffmann J, Lux A, Reinhold D.
Lower Serum Zinc Levels in Patients with Multiple Sclerosis Compared to Healthy Controls.
Nutrients. 2018 Jul 26;10(8). pii: E967. doi: 10.3390/nu10080967.
Schlör A, Holzlöhner P, Listek M, Grieß C, Butze M, Micheel B, Hentschel C, Sowa M, Roggenbuck D, Schierack P, Füner J, Schliebs E, Goihl A, Reinhold D, Hanack K.
Generation and validation of murine monoclonal and camelid recombinant single domain antibodies specific for human pancreatic glycoprotein 2.
N Biotechnol. 2018 Apr 7. pii: S1871-6784(17)30269-8. doi: 10.1016/j.nbt.2018.03.006. [Epub ahead of print]
Straubel D, Thielitz A, Reinhold A, Grüngreiff K, Reinhold D.
Combined Treatment with Zinc Aspartate and Intravenous Immunoglobulins (IVIGs) Ameliorates Experimental Autoimmune Encephalomyelitis (EAE).
J Immunol Res. 2018 Sep 26;2018:5982169. doi: 10.1155/2018/5982169. eCollection 2018
Zhang S, Luo J, Wu Z, Roggenbuck D, Schierack P, Reinhold D, Li J, Zeng X, Zhang F, Qian J, Li Y.
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal Behçet's disease.
Clin Transl Gastroenterol. 2018 Feb 15;9(2):e133. doi: 10.1038/ctg.2018.1.
2017
Körtvelyessy P, Bartels C, Galazky I, Ranft K, Sailer M, Schreiber SJ, Heinsius V, Reinhold D, Vielhaber S, Heinze HJ, Huchtemann T.
Der neurologische Boomerang nach Herpes-Simples-Enzephalitis.
Klin. Neurophysiol. 2017; 48: 44-45.
Mirdamadi Y, Bommhardt U, Goihl A, Guttek K, Zouboulis CC, Quist S, Gollnick H.
Insulin and Insulin-like growth factor-1 can activate the phosphoinositide-3-kinase /Akt/FoxO1 pathway in T cells in vitro.
Dermato-Endocrinology 2017, DOI: 10.1080/19381980.2017.1356518
Mirdamadi Y, Thielitz A, Wiede A, Goihl A, Zouboulis CC, Bommhardt U, Quist S, Gollnick H.
Effects of Isotretinoin on the Phosphoinositide-3-kinase/Akt/FoxO1 Pathway and Molecular Functions of SZ95 Sebocytes In vitro.
J Clin Exp Dermatol Res 2017. doi:10.4172/2155-9554.1000399
Ranjan S, Goihl A, Kohli S, Gadi I, Pierau M, Shahzad K, Gupta D, Bock F, Wang H, Shaikh H, Kähne T, Reinhold D, Bank U, Zenclussen AC, Niemz J, Schnöder TM, Brunner-Weinzierl M, Fischer T, Kalinski T, Schraven B, Luft T, Huehn J, Naumann M, Heidel FH, Isermann B.
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells.
Nat Commun. 2017 Aug 21;8(1):311. doi: 10.1038/s41467-017-00169-4.
Röber N, Noß L, Goihl A, Reinhold D, Jahn J, de Laffolie J, Johannes W, Flemming GM, Roggenbuck D, Conrad K, Laass MW.
Autoantibodies Against Glycoprotein 2 Isoforms in Pediatric Patients with Inflammatory Bowel Disease.
Inflamm Bowel Dis. 2017 Sep;23(9):1624-1636. doi: 10.1097/MIB.0000000000001159.
Roggenbuck D, Goihl A, Hanack K, Holzlöhner P, Hentschel C, Veiczi M, Schierack P, Reinhold D, Schulz HU.
Serological diagnosis and prognosis of severe acute pancreatitis by analysis of serum glycoprotein 2.
Clin Chem Lab Med. 2017 May 1;55(6):854-864. doi: 10.1515/cclm-2016-0797.
von Arnim U, Röhl FW, Miehlke S, Jechorek D, Reinhold D, Wex T, Malfertheiner P.
Letter: multivariate clinical model for eosinophilic oesophagitis - is this generalisable to a general population? Authors' reply.Aliment Pharmacol Ther. 2017 Mar;45(6):861. doi: 10.1111/apt.13967. No abstract available.
von Arnim U, Röhl FW, Miehlke S, Jechorek D, Reinhold D, Wex T1, Malfertheiner P.
Clinical symptom tool that raises the index of suspicion for eosinophilic oesophagitis in adults and drives earlier biopsy for definitive diagnosis.
Aliment Pharmacol Ther. 2017 Feb;45(3):417-426. doi: 10.1111/apt.13869. Epub 2016 Nov 29.
2016
Fatahi M, Reddig A, Vijayalaxmi, Friebe B, Hartig R, Prihoda TJ, Ricke J, Roggenbuck D, Reinhold D, Speck O.
DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging.
Neuroimage. 2016 Mar 16;133:288-293. doi: 10.1016/j.neuroimage.2016.03.023.
Grossmann K, Röber N, Hiemann R, Rödiger S, Schierack P, Reinhold D, Laass MW, Conrad K, Roggenbuck D.
Simultaneous detection of celiac disease-specific IgA antibodies and total IgA.
Auto Immun Highlights. 2016 Dec;7(1):2. doi: 10.1007/s13317-016-0073-2. Epub 2016 Jan 30.
Grüngreiff K, Reinhold D, Wedemeyer H.
The role of zinc in liver cirrhosis.
Ann Hepatol. 2015 Jan-2016 Feb;15(1):7-16.
Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schlüter D, Reinhold D, Jordan BA, Gintschel P, Schraven B, Kreutz MR.
Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice.
PLoS One. 2016 Sep 22;11(9):e0162863.
Lowinus T, Bose T, Busse S, Busse M, Reinhold D, Schraven B, Bommhardt UH.
Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness.
Oncotarget. 2016 Jul 22. doi: 10.18632/oncotarget.10777. [Epub ahead of print]
Mürke E, Stoll S, Lendeckel U, Reinhold D, Schild L.
The mitochondrial phospholipid cardiolipin is involved in the regulation of T-cell proliferation.
Biochim Biophys Acta. 2016 Aug;1861(8 Pt A):748-54. doi: 10.1016/j.bbalip.2016.05.001. Epub 2016 May 7.
Sowa M, Hiemann R, Schierack P, Reinhold D, Conrad K, Roggenbuck D.
Next-Generation Autoantibody Testing by Combination of Screening and Confirmation-the CytoBead® Technology.
Clin Rev Allergy Immunol. 2016 Jul 2. [Epub ahead of print] Review.
Sack U, Boldt A, Mallouk N, Gruber R, Krenn V, Berger-Depincé AE, Conrad K, Tarnok A, Lambert C, Reinhold D, Fricke S.
Cellular analyses in the monitoring of autoimmune diseases.
Autoimmun Rev. 2016 Jul 5. pii: S1568-9972(16)30145-8. doi: 10.1016/j.autrev.2016.07.010. [Epub ahead of print]
Venerito M, Varbanova M, Röhl FW, Reinhold D, Frauenschläger K, Jechorek D, Weigt J, Link A, Malfertheiner P.
Oxyntic gastric atrophy in Helicobacter pylori gastritis is distinct from autoimmune gastritis.
J Clin Pathol. 2016 Jan 4. pii: jclinpath-2015-203405. doi: 10.1136/jclinpath-2015-203405. [Epub ahead of print]
2015
Engelmann S, Togni M, Kliche S, Reinhold D, Schraven B, Reinhold A.
The adhesion- and degranulation-promoting adaptor protein and its role in the modulation of experimental autoimmune encephalomyelitis.
Crit Rev Immunol. 2015;35(1):1-14.
Mirdamadi Y, Thielitz A, Wiede A, Goihl A, Papakonstantinou E, Hartig R, Zouboulis CC, Reinhold D, Simeoni L, Bommhardt U, Quist S, Gollnick H.
Insulin and Insulin-like growth factor-1 Can Modulate the Phosphoinositide-3-kinase / Akt/ FoxO1 Pathway in SZ95 Sebocytes in vitro.
Mol Cell Endocrinol. 2015 Aug 6. pii: S0303-7207(15)30041-1. doi: 10.1016/j.mce.2015.08.001. [Epub ahead of print]
Reddig A, Fatahi M, Friebe B, Guttek K, Hartig R, Godenschweger F, Roggenbuck D, Ricke J, Reinhold D, Speck O.
Analysis of DNA Double-Strand Breaks and Cytotoxicity after 7 Tesla Magnetic Resonance Imaging of Isolated Human Lymphocytes.
PLoS One. 2015 Jul 15;10(7):e0132702. doi: 10.1371/journal.pone.0132702. eCollection 2015.
Reddig A, Lorenz S, Hiemann R, Guttek K, Hartig R, Heiserich L, Eberle C, Peters V, Schierack P, Sack U, Roggenbuck D, Reinhold D.
Assessment of modulated cytostatic drug resistance by automated γH2AX analysis.
Cytometry A. 2015 Apr 2. doi: 10.1002/cyto.a.22667. [Epub ahead of print]
Reddycherla AV, Meinert I, Reinhold A, Reinhold D, Schraven B, Simeoni L.
miR-20a Inhibits TCR-Mediated Signaling and Cytokine Production in Human Naïve CD4+ T Cells.
PLoS One. 2015 Apr 17;10(4):e0125311. doi: 10.1371/journal.pone.0125311. eCollection 2015.
Scholz J, Grossmann K, Knütter I, Hiemann R, Sowa M, Röber N, Rödiger S, Schierack P, Reinhold D, Bogdanos DP, Meroni PL, Radice A, Conrad K, Roggenbuck D.
Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing.
Clin Chem Lab Med. 2015 Nov 1;53(12):1991-2002. doi: 10.1515/cclm-2015-0083.
2014
Ewald F, Annemann M, Pils MC, Plaza-Sirvent C, Neff F, Erck C, Reinhold D, Schmitz I.
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice.
Cell Death Dis. 2014 Apr 10;5:e1168. doi: 10.1038/cddis.2014.138.
Harder T, Guttek K, Philipsen L, Simeoni L, Schraven B, Reinhold D.
Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation.
Cell Commun Signal. 2014 Dec 8;12(1):74. doi: 10.1186/s12964-014-0074-6.
Reinhold D, Brocke S.
DPP4-directed therapeutic strategies for MERS-CoV.
Lancet Infect Dis. 2014 Feb;14(2):100-1. doi: 10.1016/S1473-3099(13)70696-0.
Roggenbuck D, Vermeire S, Hoffman I, Reinhold D, Schierack P, Goihl A, von Arnim U, De Hertogh G, Polymeros D, Bogdanos DP, Bossuyt X.
Evidence of Crohn's disease-related anti-glycoprotein 2 antibodies in patients with celiac disease.
Clin Chem Lab Med. 2014 Nov 20. pii: /j/cclm.ahead-of-print/cclm-2014-0238/cclm-2014-0238.xml. doi: 10.1515/cclm-2014-0238. [Epub ahead of print]
Roggenbuck D, Hiemann R, Schierack P, Reinhold D, Conrad K.
Digital immunofluorescence enables automated detection of antinuclear antibody endpoint titers avoiding serial dilution.
Clin Chem Lab Med. 2014 Feb;52(2):e9-11. doi: 10.1515/cclm-2013-0543.
Roggenbuck D, Reinhold D, Schierack P, Bogdanos DP, Conrad K, Laass MW.
Crohn's disease specific pancreatic antibodies: clinical and pathophysiological challenges.
Clin Chem Lab Med. 2014 Apr;52(4):483-94. doi: 10.1515/cclm-2013-0801.
Schubert C, Guttek K, Grüngreiff K, Thielitz A, Bühling F, Reinhold A, Brocke S, Reinhold D.
Oral zinc aspartate treats experimental autoimmune encephalomyelitis.
Biometals. 2014 Dec;27(6):1249-62. doi: 10.1007/s10534-014-9786-8. Epub 2014 Aug 22.
Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E, Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D.
Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.
PLoS One. 2014 Sep 16;9(9):e107743. doi: 10.1371/journal.pone.0107743. eCollection 2014.
Schierack P, Rödiger S, Kolenda R, Hiemann R, Berger E, Grzymajło K, Swidsinski A, Juretzek T, Meissner D, Mydlak K, Reinhold D, Nolan LK, Roggenbuck D.
Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2).
Gut. 2014 Jul 29. pii: gutjnl-2014-307854. doi: 10.1136/gutjnl-2014-307854. [Epub ahead of print]
Wex T, Grungreiff K, Schutte K, Stengritt M, Reinhold D.
Expression analysis of zinc transporters in resting and stimulated human peripheral blood mononuclear cells.
Biomed Rep. 2014 Mar;2(2):217-222. Epub 2014 Jan 13.
2013
Arndt B, Kalinski T, Reinhold D, Thielitz A, Roessner A, Schraven B, Simeoni L.
Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX.
J Leukoc Biol. 2013 Mar;93(3):353-62. doi: 10.1189/jlb.0312152. Epub 2013 Jan 10.
Roggenbuck D, Reinhold D, Werner L, Schierack P, Bogdanos DP, Conrad K.
Glycoprotein 2 antibodies in Crohn's disease.
Adv Clin Chem. 2013;60:187-208.
Roggenbuck D, Humbel RL, Reinhold D, Bogdanos DP, Conrad K, Laass MW.
Glycoprotein 2 antibodies in inflammatory bowel disease: no association with disease phenotype?
J Pediatr Gastroenterol Nutr. 2013 Jan;56(1):e5. doi: 10.1097/MPG.0b013e318275fa77.
Roggenbuck D, Hiemann R, Bogdanos D, Reinhold D, Conrad K.
Standardization of automated interpretation of immunofluorescence tests.
Clin Chim Acta. 2013 Jun 5;421:168-9. doi: 10.1016/j.cca.2013.03.019. Epub 2013 Mar 26.
Willitzki A, Lorenz S, Hiemann R, Guttek K, Goihl A, Hartig R, Conrad K, Feist E, Sack U, Schierack P, Heiserich L, Eberle C, Peters V, Roggenbuck D, Reinhold D.
Fully automated analysis of chemically induced γH2AX foci in human peripheral blood mononuclear cells by indirect immunofluorescence.
Cytometry A. 2013 Sep 5. doi: 10.1002/cyto.a.22350. [Epub ahead of print]
2012
Bogdanos DP, Roggenbuck D, Reinhold D, Wex T, Pavlidis P, von Arnim U, Malfertheiner P, Forbes A, Conrad K, Laass MW.
Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn's disease.
BMC Gastroenterol. 2012 Aug 6;12:102.
Conrad K, Roggenbuck D, Ittenson A, Reinhold D, Buettner T, Laass MW.
A new dot immunoassay for simultaneous detection of celiac specific antibodies and IgA-deficiency.
Clin Chem Lab Med. 2012 Feb;50(2):337-43. doi: 10.1515/cclm.2011.760.
Conrad K, Roggenbuck D, Reinhold D, Sack U.
Autoantibody diagnostics in clinical practice.
Autoimmun Rev. 2012 Jan;11(3):207-11. Epub 2011 May 18.
Goihl A, Rolle AM, Kähne T, Reinhold A, Wrenger S, Reinhold D.
Methodologic issues in the measurement of interleukin-16 in clinical blood samples using immunoassays.
Cytokine. 2012 Apr;58(1):1-5. Epub 2012 Jan 11.
Lapp T, Reinhold D, Maier P, Reinhard T.
[Old immune system - New information? : Importance of mononuclear phagocytes in corneal allograft rejection.]
Ophthalmologe. 2012 Apr 13. [Epub ahead of print] German.
Röhnert P, Schmidt W, Emmerlich P, Goihl A, Wrenger S, Bank U, Nordhoff K, Täger M, Ansorge S, Reinhold D, Striggow F.
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia.
J Neuroinflammation. 2012 Feb 28;9:44.
Stoye D, Schubert C, Goihl A, Guttek K, Reinhold A, Brocke S, Grüngreiff K, Reinhold D.
Zinc aspartate suppresses T cell activation in vitro and relapsing experimental autoimmune encephalomyelitis in SJL/J mice.
Biometals. 2012 Jun;25(3):529-39. Epub 2012 Feb 19.
Thielitz A, Bellutti M, Bonnekoh B, Franke I, Wiede A, Lotzing M, Reinhold D, Gollnick H.
Progressive lipo-lymphedema associated with increased activity of dermal fibroblasts in monoclonal gammopathy of undetermined significance: is there a causal relationship?
Lymphology. 2012 Sep;45(3):124-9.
Togni M, Engelmann S, Reinhold D, Schraven B, Reinhold A.
The adapter protein ADAP is required for selected dendritic cell functions.
Cell Commun Signal. 2012 Jun 6;10(1):14.
Werner L, Paclik D, Fritz C, Reinhold D, Roggenbuck D, Sturm A.
Identification of pancreatic glycoprotein 2 as an endogenous immunomodulator of innate and adaptive immune responses.
J Immunol. 2012 Sep 15;189(6):2774-83. doi: 10.4049/jimmunol.1103190. Epub 2012 Aug 13.
Wienecke J, Hebel K, Hegel KJ, Pierau M, Brune T, Reinhold D, Pethe A, Brunner-Weinzierl MC.
Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus.
Placenta. 2012 Jan;33(1):39-46. Epub 2011 Nov 16.
2011
Ansorge S, Nordhoff K, Bank U, Heimburg A, Julius H, Breyer D, Thielitz A, Reinhold D, Täger M.
Novel aspects of cellular action of dipeptidyl peptidase IV/CD26
Biol Chem. 2011 Mar;392(3):153-68
Bank U, Heimburg A, Wohlfarth A, Koch G, Nordhoff K, Julius H, Helmuth M, Breyer D, Reinhold D, Täger M, Ansorge S.
Outside or inside: role of the subcellular localization of DP4-like enzymes for substrate conversion and inhibitor effects
Biol Chem. 2011 Mar;392(3):169-87
Biton A, Ansorge S, Bank U, Täger M, Reinhold D, Brocke S.
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions.
Immunobiology. 2011 Dec;216(12):1295-301. Epub 2011 Jul 7.
Bogdanos DP, Rigopoulou EI, Smyk DS, Roggenbuck D, Reinhold D, Forbes A, Laass MW, Conrad K.
Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies.
Autoimmun Rev. 2011 Dec;11(2):143-8.
Haroon F, Drögemüller K, Händel U, Brunn A, Reinhold D, Nishanth G, Mueller W, Trautwein C, Ernst M, Deckert M, Schlüter D.
Gp130-dependent astrocytic survival is critical for the control of autoimmune central nervous system inflammation.
J Immunol. 2011 Jun 1;186(11):6521-31. Epub 2011 Apr 22.
Hölzl MA, Hofer J, Kovarik JJ, Roggenbuck D, Reinhold D, Goihl A, Gärtner M, Steinberger P, Zlabinger GJ.
The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I)
Cell Immunol. 2011;267(2):88-93. Epub 2010 Dec 8
Reinhold D, Bank U, Entz D, Goihl A, Stoye D, Wrenger S, Brocke S, Thielitz A, Stefin S, Nordhoff K, Heimburg A, Täger M, Ansorge S.
PETIR-001, a dual inhibitor of dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN), ameliorates experimental autoimmune encephalomyelitis in SJL/J mice
Biol Chem. 2011 Mar;392(3):233-7
Roggenbuck D, Reinhold D, Hiemann R, Anderer U, Conrad K.
Standardized detection of anti-ds DNA antibodies by indirect immunofluorescence - a new age for confirmatory tests in SLE diagnostics.
Clin Chim Acta. 2011 Oct 9;412(21-22):2011-2.
Roggenbuck D, Reinhold D, Wex T, Goihl A, von Arnim U, Malfertheiner P, Büttner T, Porstmann T, Porstmann S, Liedvogel B, Bogdanos DP, Laass MW, Conrad K.
Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease.
Clin Chim Acta. 2011 Apr 11;412(9-10):718-24. Epub 2010 Dec 31.
2010
Conrad K, Roggenbuck D, Reinhold D, Dörner T.
Profiling of rheumatoid arthritis associated autoantibodies.
Autoimmun Rev. 2010 Apr;9(6):431-5.
Grüngreiff K, Reinhold D.
Zinc: A complementary factor in the treatment of chronic hepatitis C? (Review).
Mol Med Report. 2010 May-Jun;3(3):371-5.
Roggenbuck D, Conrad K, Reinhold D.
High sensitive detection of double-stranded DNA antibodies by a modified Crithidia luciliae immunofluorescence test may improve diagnosis of systemic lupus erythematosus.
Clin Chim Acta. 2010 Nov 11;411(21-22):1837-8. Epub 2010 Jul 25.