INSTITUT FÜR MOLEKULARE UND KLINISCHE IMMUNOLOGIE

Publikationen vor 2010

2009

Bajbouj K, Poehlmann A, Kuester D, Drewes T, Haase K, Hartig R, Teller A, Kliche S, Walluscheck D, Ivanovska J, Chakilam S, Ulitzsch A, Bommhardt U, Leverkus M, Roessner A, Schneider-Stock R.
Identification of phosphorylated p38 as a novel DAPK-interacting partner during TNFalpha-induced apoptosis in colorectal tumor cells.
Am J Pathol. 2009 Aug;175(2):557-70.

*Horn J, *Wang X, Reichardt P, Stradal TE, Warnecke N, Simeoni L, Gunzer M, Yablonski D, Schraven B, Kliche S.
Src homology 2-domain containing leukocyte-specific phosphoprotein of 76 kDa Is mandatory for TCR-mediated inside-out signaling, but dispensable for CXCR4-mediated LFA-1 activation, adhesion, and migration of T cells.
J Immunol. 2009 Nov 1;183(9):5756-67. (*Horn and Wang epually contributed to the publication.)

2008

Posevitz-Fejfár A, Smída M, Kliche S, Hartig R, Schraven B, Lindquist JA.
A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration.
Eur J Immunol. 2008 Jan;38(1):250-9.

Waibler Z, Sender L, Merten C, Hartig R, Kliche S, Gunzer M, Reichardt P, Kalinke U, Schraven B.
Signaling signatures and functional properties of anti-human CD28 superagonistic antibodies.
PLoS ONE. 2008 Mar 5;3(3):e1708.

Wang X, Simeoni L, Lindquist JA, Saez-Rodriguez J, Ambach A, Gilles ED, Kliche S, Schraven B.
Dynamics of Proximal Signaling Events after TCR/CD8-Mediated Induction of Proliferation or Apoptosis in Mature CD8+ T Cells.
J Immunol. 2008 May 15;180(10):6703-12.

2007

Jordan MS, Maltzman JS, Kliche S, Shabason J, Smith JE, Obstfeld A, Schraven B, Koretzky GA.
In vivo disruption of T cell development by expression of a dominant-negative polypeptide designed to abolish the SLP-76/Gads interaction.
Eur J Immunol. 2007 Oct;37(10):2961-72.

Menasche G, Kliche S, Bezmann N, Schraven B.
Regulation of T-cell antigen receptor-mediated inside-out signaling by cytosolic adapter proteins and Rap1 effector molecules.
Immunol Rev. 2007 Aug;218:82-91.

Menasche G, Kliche S, Chen EJ, Stradal TE, Schraven B, Koretzky G.
RIAM Links the ADAP/SKAP-55 Signaling Module to Rap1 Facilitating TCR-Mediated Integrin Activation.
Mol Cell Biol. 2007 Jun;27(11):4070-81.

2006

Heuer K, Sylvester M, Kliche S, Pusch R, Thiemke K, Schraven B, Freund C.
Lipid-binding hSH3 domains in immune cell adapter proteins.
J Mol Biol. 2006 Aug 4;361(1):94-104.

Kliche S, Breitling D, Togni M, Pusch R, Heuer K, Wang X, Freund C, Kasirer-Friede A, Menasche G, Koretzky GA, Schraven B.
The ADAP/SKAP55 Signaling Module Regulates T-Cell Receptor-Mediated Integrin Activation through Plasma Membrane Targeting of Rap1.
Mol Cell Biol. 2006 Oct;26(19):7130-44.

Stradal TE, Pusch R, Kliche S.
Molecular regulation of cytoskeletal rearrangements during T cell signalling.
Results Probl Cell Differ. 2006;43:219-44.

2005

Togni M, Swanson KD, Reimann S, Kliche S, Pearce AC, Simeoni L, Reinhold D, Wienands J, Neel BG, Schraven B, Gerber A.
Regulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM.
Mol Cell Biol. 2005 Sep;25(18):8052-63. download pdf

von Wichert G, Haeussler U, Greten FR, Kliche S, Dralle H, Böhm BO, Adler G, Seufferlein T.
Regulation of cyclin D1 expression by autocrine IGF-I in human BON neuroendocrine tumour cells.
Oncogene. 2005 Feb 10;24(7):1284-9. download pdf

2004

Kliche S, Lindquist JA, Schraven B.
Transmembrane adapters: structure, biochemistry and biology.
Semin Immunol. 2004 Dec;16(6):367-77.

Simeoni L, Kliche S, Lindquist J, Schraven B.
Adaptors and linkers in T and B cells.
Curr Opin Immunol. 2004 Jun;16(3):304-13.

Togni M, Lindquist J, Gerber A, Kölsch U, Hamm-Baarke A, Kliche, S, Schraven B.
The role of adaptor proteins in lymphocyte activation.
Mol Immunol. 2004;41:615-630.

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