2024

Bhuria V, Franz T, Baldauf C, Böttcher M, Chatain N, Koschmieder S, Brümmendorf TH, Mougiakakos D, Schraven B, Kahlfuß S, Fischer T.
Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry.
Cell Commun Signal. 2024 Mar 21;22(1):186. doi: 10.1186/s12964-024-01530-z.

Brandt S, Bernhardt A, Häberer S, Wolters K, Gehringer F, Reichardt C, Krause A, Geffers R, Kahlfuß S, Jeron A, Bruder D, Lindquist JA, Isermann B, Mertens PR.
Comparative Analysis of Acute Kidney Injury Models and Related Fibrogenic Responses: Convergence on Methylation Patterns Regulated by Cold Shock Protein.
Cells. 2024 Feb 20;13(5):367.

Franz T, Stegemann-Koniszewski S, Schreiber J, Müller A, Bruder D, Dudeck A, Boehme JD, Kahlfuss S.
Metabolic and ionic control of T cells in asthma endotypes.
Am J Physiol Cell Physiol. 2024 Oct 7. doi: 10.1152/ajpcell.00474.2024. Online ahead of print.

Genseke S, Berisha M, Teerstegen A, Meyer B, Kaasch AJ, Färber J, Schalk E, Zautner AE, Esser T, Kahlfuß S.
Lautropia mirabilis sepsis in immunodeficiency: first report and genomic features.
Infection. 2024 Sep 6. doi: 10.1007/s15010-024-02388-6. Online ahead of print.

Kahlfuss S, Paggetti J, Böttcher M.
Editorial: Metabolic barriers in cancer and cancer therapy.
Front Oncol. 2024 May 8;14:1411579.

Kotrba J, Müller I, Pausder A, Hoffmann A, Camp B, Boehme JD, Müller A, Schreiber J, Bruder D, Kahlfuss S, Dudeck A, Stegemann-Koniszewski S.
Innate players in Th2 and non-Th2 asthma - emerging roles for the epithelial cell, mast cell and monocyte/macrophage network.
Am J Physiol Cell Physiol. 2024 Oct 14. doi: 10.1152/ajpcell.00488.2024. Online ahead of print.

Reichardt C, Brandt S, Bernhardt A, Krause A, Lindquist JA, Weinert S, Geffers R, Franz T, Kahlfuss S, Dudeck A, Mathew A, Rana R, Isermann B, Mertens PR.
DNA-binding protein-A promotes kidney ischemia/reperfusion injury and participates in mitochondrial function.
Kidney Int. 2024 May 29:S0085-2538(24)00379-X. Epub ahead of print.

2023

Baars I, Jaedtka M, Dewitz LA, Fu Y, Franz T, Mohr J, Gintschel P, Berlin H, Degen A, Freier S, Rygol SM, Schraven B, Kahlfuss S, van Zandbergen G, Müller AJ.
Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate.
JCI Insight. 2023 Jun 13:e169020.

Binder R, Hahn A, Eberhardt KA, Hagen RM, Rohde H, Loderstädt U, Feldt T, Sarfo FS, Di Cristanziano V, Kahlfuss S, Frickmann H, Zautner AE.
Comparison of the Diagnostic Accuracy of Three Real-Time PCR Assays for the Detection of Arcobacter butzleri in Human Stool Samples Targeting Different Genes in a Test Comparison without a Reference Standard.
Microorganisms. 2023 May 17;11(5):1313.

Hoffmann K, Riediger M, Tersteegen A, Marquardt P, Kahlfuß S, Kaasch AJ, Hagen RM, Frickmann H, Zautner AE.
Molecular epidemiology of enterically colonizing Escherichia coli with resistance against third-generation cephalosporins isolated from stool samples of European soldiers with concomitant diarrhea on deployment in Western African Mali.
Front Microbiol. 2023 May 5;14:1169829.

Kruse B, Buzzai AC, Shridhar N, Braun AD, Gellert S, Knauth K, Pozniak J, Peters J, Dittmann P, Mengoni M, van der Sluis TC, Höhn S, Antoranz A, Krone A, Fu Y, Yu D, Essand M, Geffers R, Mougiakakos D, Kahlfuß S, Kashkar H, Gaffal E, Bosisio FM, Bechter O, Rambow F, Marine JC, Kastenmüller W, Müller AJ, Tüting T.
CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours.
Nature. 2023 Jun 14.

Jantz-Naeem N, Böttcher-Loschinski R, Borucki K, Mitchell-Flack M, Böttcher M, Schraven B, Mougiakakos D, Kahlfuss S.
TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment.
Front Oncol. 2023 Feb 17;13:1060112.

Roder M^#, Franz T^#, Negele J^#, Schreiber J*, Kahlfuss S*.
Asthma bronchiale - Unterschiedliche Endotypen, unterschiedliche Therapien.
Deutsches Ärzteblatt. 2023. Dtsch Arztebl 2023; 120(15): [18]. *Corr. authors #First-authors

2022

Böttcher-Loschinski R, Rial Saborido J, Böttcher M, Kahlfuss S, Mougiakakos D.
Lipotoxicity as a Barrier for T Cell-Based Therapies.
Biomolecules. 2022; 12(9):1182.

Böttcher M, Böttcher-Loschinski R, Kahlfuss S, Aigner M, Gießl A, Mackensen A, Schlötzer-Schrehardt U, Tüting T, Bruns H, Mougiakakos D.
CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints.
Cells. 2022 Jul 12;11(14):2176.

Franz T, Negele J, Bruno P, Böttcher M, Mitchell-Flack M, Reemts L, Krone A, Mougiakakos D, Müller AJ, Zautner AE, Kahlfuss S.
Pleiotropic effects of antibiotics on T cell metabolism and T cell-mediated immunity.
Front Microbiol. 2022 Oct 18;13:975436.

Franz T^#, Negele J^#, Kahlfuss S.
Cytotoxic innate lymphoid cells sense tumor-derived IL-15: A novel mechanism of cancer immunosurveillance.
Signal Transduct Target Ther. 2022 Sep 17;7(1):326. #Co-First authors

Krone A, Fu Y, Schreiber S, Kotrba J, Borde L, Nötzold A, Thurm C, Negele J, Franz T, Stegemann-Koniszewski S, Schreiber J, Garbers C, Shukla A, Geffers R, Schraven B, Reinhold D, Dudeck A, Reinhold A, Müller AJ, Kahlfuss S.
Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc.
Sci Rep. 2022 Feb 4;12(1):1943. doi: 10.1038/s41598-022-04827-6.

Negele J^#, Franz T^#, Kahlfuss S*.
T-Zell-Metabolismus: Potenzial für Diagnostik und Therapie
Trillium Diagnostik, 2/2022. #First-authors *Corresponding author

Roder M, Kahlfuss S*.
Implementation of Immunometabolism into Curricula, Scientific Societies, and Immunological Routine Diagnostics.
J Immunol Sci. 2022 Dec 19. *Corr. author

Thurm C, Reinhold A, Borucki K, Kahlfuss S, Feist E, Schreiber J, Reinhold D, Schraven B.
Homologous and Heterologous Anti-COVID-19 Vaccination Does Not Induce New-Onset Formation of Autoantibodies Typically Accompanying Lupus Erythematodes, Rheumatoid Arthritis, Celiac Disease and Antiphospholipid Syndrome.
Vaccines (Basel). 2022 Feb 18;10(2):333.

Wang Y-H^#, Noyer L^#, Kahlfuss S^#, Raphael D, Tao AJ, Kaufmann U, Zhu J, Mitchell-Flack M, Sidhu I, Zhou F, Vaeth M, Thomas PG, Saunders SP, Stauderman K, Curotto de Lafaille MA, Feske S.
Distinct roles of ORAI1 in T cell-mediated allergic airway inflammation and immunity to influenza A virus infection.
 Sci Adv. 2022 Oct 7;8(40):eabn6552. #Co-First authors

2021

Formaglio P, Alabdullah M, Siokis A, Handschuh J, Sauerland I, Fu Y, Krone A, Gintschel P, Stettin J, Heyde S, Mohr J, Philipsen L, Schröder A, Robert PA, Zhao G, Khailaie S, Dudeck A, Bertrand J, Späth GF, Kahlfuß S, Bousso P, Schraven B, Huehn J, Binder S, Meyer-Hermann M, Müller AJ.
Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells.
Immunity. 2021 Oct 15:S1074-7613(21)00406-4. doi: 10.1016/j.immuni.2021.09.021. Online ahead of print. IF: 31.745

Mougiakakos D, Kahlfuss S.
"Moonlighting" at the power plant: how mitochondria facilitate serial killing by CD8+ cytotoxic T cells.
Signal Transduct Target Ther. 2021 Dec 22;6(1):436. doi: 10.1038/s41392-021-00846-3. IF: 18.187

Reinhold D, Guttek K, Reddig A, Voss L, Schubert C, Kahlfuss S, Grüngreiff K, Schraven B, Reinhold A.
Zinc Aspartate Induces IL-16 Secretion and Apoptosis in Human T Cells.
Biomedicines. 2021 Mar 1;9(3):246. doi: 10.3390/biomedicines9030246. IF: 6.081

Schreiber S, Hammers CM, Kaasch AJ, Schraven B, Dudeck A, Kahlfuss S.
Metabolic Interdependency of Th2 Cell-Mediated Type 2 Immunity and the Tumor Microenvironment.
Frontiers in Immunology. 2021 May 31;12:632581. doi: 10.3389/fimmu.2021.632581. eCollection 2021. IF: 7.561

Thurm C, Schraven B, Kahlfuss S.
ABC Transporters in T Cell-Mediated Physiological and Pathological Immune Responses.
Int J Mol Sci. 2021 Aug 25;22(17):9186. doi: 10.3390/ijms22179186. IF:5.932

2020

Kahlfuss S, Kaufmann U, Concepcion A, Noyer L, Raphael D, Vaeth M, Yang J, Pancholi P, Maus M, Muller J, Kozhaya L, Khodadadi-Jamayran A, Sun Z, Shaw P, Unutmaz U, Stathopulos BP, Feist C, Cameron S, Turvey S, Feske S.
STIM1-mediated calcium influx controls antifungal immunity by regulating the metabolic function of non-pathogenic Th17 cells.
EMBO Molecular Medicine. 2020. IF: 10.624

Vaeth M, Kahlfuss S, Feske S.
CRAC channels and CalciumInflux in T Cell-Mediated Immunity.
Trends in Immunology. 2020. IF: 13.000

2019

Kaufmann U*, Kahlfuss S*, Yang J, Ivanova E, Koralov SB, Feske S.
Calcium signaling controls pathogenic Th17 cell-mediated inflammation by regulating mitochondrial function.
Cell Metabolism. 2019. *Co-Firstauthor IF: 22.415

2018

Lian J*, Cuk M *, Kahlfuss S*, Kozhaya L, Vaeth M, Rieux-Laucat F, Picard C, Benson MJ, Jakovcevic A, Bilic K, Martinac I, Stathopulos P, Kacskovics I, Vraetz T, Speckmann C, Ehl S, Issekutz T, Unutmaz D, Feske S.
ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency.
Journal of Allergy and Clin. Immunology. 2018 *Co-Firstauthor IF: 14.100

2014

Kahlfuss S*, Simma N*, Mankiewicz J*, Bose T*, Lowinus T, Klein-Hessling S, Sprengel R, Schraven B, Heine M, Bommhardt U.
Immunosuppression by N-methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells.
Molecular and Cellular Biology. 2014. IF: 3.735